The Ultimate Guide to Microneedling with PRF for Radiant Skin

Radiant skin isn’t about covering up—it’s about supporting your body’s natural ability to repair and regenerate. At Cary Care Esthetics in Cary, NC, we use microneedling with PRF (Platelet Rich Fibrin) to help your skin do just that. By combining the collagen-stimulating power of microneedling with the regenerative benefits of your own blood, this treatment softens wrinkles, improves tone, and brings out a healthier, smoother complexion. It’s a gentle but powerful option for anyone wanting refreshed skin without harsh chemicals or extended downtime.

What Is Microneedling with PRF?

Microneedling creates tiny channels in the skin, triggering your body’s natural repair process. When PRF is applied, these microchannels become a pathway for your own growth factors to go to work—stimulating new collagen, increasing skin elasticity, and boosting hydration from the inside out.

PRF is spun from your blood at a low speed, preserving a higher concentration of platelets, white blood cells, and stem cells. Unlike PRP (Platelet Rich Plasma), PRF doesn’t require anticoagulants or additives, which makes it more natural and slower releasing. That slow release means longer-lasting, deeper rejuvenation.

Who Is This Treatment For?

People visit us for microneedling with PRF for all sorts of reasons. Some are getting ready for weddings or big events and want that healthy skin glow. Others are treating long-term concerns like acne scars, dullness, or sun damage. We also work with clients managing hormonal shifts, postpartum changes, and early signs of aging.

If your skin feels tired, thin, or uneven—or if you’re just ready for a refresh without looking overdone—this could be the right fit.

What Does Microneedling with PRF Help With?

Microneedling with PRF is incredibly versatile. It’s one of our most requested treatments because it addresses so many concerns with one approach.

Here’s what it can help improve:

  • Fine lines and wrinkles
  • Sagging or thinning skin
  • Under-eye hollows and darkness
  • Acne scars and large pores
  • Uneven tone or skin pigmentation
  • Dull, dry skin
  • Sun spots and age spots
  • Hair loss or thinning on the scalp
  • Skin around the lips or mouth that’s starting to lose firmness

We also offer intra-oral lasering and lip lasering to further tighten and brighten the skin around the mouth—popular add-ons for patients looking to refresh their lower face.

What to Expect During the Treatment

The treatment starts with a small blood draw. From there, we process your blood to extract the PRF. The microneedling itself is precise and targeted, using a handheld device that creates micro-injuries across the surface of your skin. These are not deep enough to cause damage, but just enough to signal your skin to repair.

The PRF is either applied topically during the treatment or injected into targeted areas—especially helpful for areas like under the eyes or around the mouth. Most sessions take about an hour, and while your skin may be pink for a day or two, downtime is minimal. You can return to most of your usual activities shortly after.

Our Most Popular Skin Pairings

At Cary Care Esthetics, many of our clients combine microneedling with other non-invasive options to achieve even better results. Some pairings work beautifully for specific concerns:

  • For tightening and lifting: Viora V-FR (fractional radiofrequency) or Viora V-ST
  • For brightening and pigment correction: V-IPL photofacial or Fotona laser
  • For hydration and glow: Préime DermaFacial and IV hydration therapy
  • For volume support: Bio-filler with PRF or Botox

These treatments are customized based on your goals, whether that’s firmer skin, more even tone, or long-term collagen support. And because they’re all non-surgical, they fit into even the busiest lifestyle.

Build Your Post-Treatment Beauty Bag

A few thoughtful items can make all the difference in helping your skin recover quickly and beautifully. We suggest keeping the following on hand after your microneedling with PRF session:

  • Fragrance-free, gentle cleanser
  • Lightweight hyaluronic acid serum
  • Mineral sunscreen (SPF 30 or higher)
  • Soothing moisturizer with ceramides
  • Silk pillowcase for reduced friction
  • Collagen-support supplements or IV therapy

Our team will walk you through exactly what your skin needs based on your specific treatment plan.

When It Comes to Natural-Looking Results, Less Is More

The beauty of PRF is that it works with your body—not against it. You won’t look frozen or “done.” Instead, people may simply ask if you’ve been sleeping better or taking a great vacation. It’s subtle in the best way.

Many clients see results after just one session, but we typically recommend a series of treatments for optimal collagen rebuilding and long-term skin health.

Why Cary Care Esthetics?

Dr. Charles Ferzli has been serving the Cary, NC community for decades with a holistic approach to head, neck, and facial care. His interest in natural healing and facial esthetics grew from his dental practice, where he first began using PRF to assist with tissue regeneration. That same passion now drives the care we offer at Cary Care Esthetics.

Our focus is on using your body’s own healing capacity to restore and refresh—without relying on synthetic additives or harsh procedures. We’re here to support you with thoughtful, honest guidance and personalized care that puts your skin’s long-term health first.

If you’re in the Cary area and looking for a natural way to smooth, firm, and brighten your skin, microneedling with PRF could be a smart next step. Give us a call or schedule a consultation—we’d love to talk with you about your goals and find the right plan for your skin.